Publications

  1. Rutledge, EA, Lindström, NO, Michos, O, McMahon, AP. Genetic manipulation of ureteric bud tip progenitors in the mammalian kidney through an Adamts18 enhancer driven tet-on inducible system. Dev. Biol. 2020;458 (2):164-176. doi: 10.1016/j.ydbio.2019.11.007. PubMed PMID:31734175 PubMed Central PMC6995766.
  2. Ransick, A, Lindström, NO, Liu, J, Zhu, Q, Guo, JJ, Alvarado, GF et al.. Single-Cell Profiling Reveals Sex, Lineage, and Regional Diversity in the Mouse Kidney. Dev. Cell. 2019;51 (3):399-413.e7. doi: 10.1016/j.devcel.2019.10.005. PubMed PMID:31689386 PubMed Central PMC6948019.
  3. Tran, T, Lindström, NO, Ransick, A, De Sena Brandine, G, Guo, Q, Kim, AD et al.. In Vivo Developmental Trajectories of Human Podocyte Inform In Vitro Differentiation of Pluripotent Stem Cell-Derived Podocytes. Dev. Cell. 2019;50 (1):102-116.e6. doi: 10.1016/j.devcel.2019.06.001. PubMed PMID:31265809 PubMed Central PMC6684316.
  4. O'Brien, LL, Combes, AN, Short, KM, Lindström, NO, Whitney, PH, Cullen-McEwen, LA et al.. Wnt11 directs nephron progenitor polarity and motile behavior ultimately determining nephron endowment. Elife. 2018;7 :. doi: 10.7554/eLife.40392. PubMed PMID:30516471 PubMed Central PMC6281319.
  5. Lindström, NO, De Sena Brandine, G, Ransick, A, McMahon, AP. Single-Cell RNA Sequencing of the Adult Mouse Kidney: From Molecular Cataloging of Cell Types to Disease-Associated Predictions. Am. J. Kidney Dis. 2019;73 (1):140-142. doi: 10.1053/j.ajkd.2018.07.002. PubMed PMID:30241960 PubMed Central PMC6480390.
  6. Lindström, NO, De Sena Brandine, G, Tran, T, Ransick, A, Suh, G, Guo, J et al.. Progressive Recruitment of Mesenchymal Progenitors Reveals a Time-Dependent Process of Cell Fate Acquisition in Mouse and Human Nephrogenesis. Dev. Cell. 2018;45 (5):651-660.e4. doi: 10.1016/j.devcel.2018.05.010. PubMed PMID:29870722 PubMed Central PMC6510587.
  7. Lindström, NO, McMahon, JA, Guo, J, Tran, T, Guo, Q, Rutledge, E et al.. Conserved and Divergent Features of Human and Mouse Kidney Organogenesis. J. Am. Soc. Nephrol. 2018;29 (3):785-805. doi: 10.1681/ASN.2017080887. PubMed PMID:29449453 PubMed Central PMC5827606.
  8. Lindström, NO, Tran, T, Guo, J, Rutledge, E, Parvez, RK, Thornton, ME et al.. Conserved and Divergent Molecular and Anatomic Features of Human and Mouse Nephron Patterning. J. Am. Soc. Nephrol. 2018;29 (3):825-840. doi: 10.1681/ASN.2017091036. PubMed PMID:29449451 PubMed Central PMC5827611.
  9. Lindström, NO, Guo, J, Kim, AD, Tran, T, Guo, Q, De Sena Brandine, G et al.. Conserved and Divergent Features of Mesenchymal Progenitor Cell Types within the Cortical Nephrogenic Niche of the Human and Mouse Kidney. J. Am. Soc. Nephrol. 2018;29 (3):806-824. doi: 10.1681/ASN.2017080890. PubMed PMID:29449449 PubMed Central PMC5827607.
  10. Collinson, JM, Lindström, NO, Neves, C, Wallace, K, Meharg, C, Charles, RH et al.. The developmental and genetic basis of 'clubfoot' in the peroneal muscular atrophy mutant mouse. Development. 2018;145 (3):. doi: 10.1242/dev.160093. PubMed PMID:29439133 PubMed Central PMC5818009.
  11. Berry, RL, Ozdemir, DD, Aronow, B, Lindström, NO, Dudnakova, T, Thornburn, A et al.. Deducing the stage of origin of Wilms' tumours from a developmental series of Wt1-mutant mice. Dis Model Mech. 2015;8 (8):903-17. doi: 10.1242/dmm.018523. PubMed PMID:26035382 PubMed Central PMC4527280.
  12. Lindström, NO, Carragher, NO, Hohenstein, P. The PI3K pathway balances self-renewal and differentiation of nephron progenitor cells through β-catenin signaling. Stem Cell Reports. 2015;4 (4):551-60. doi: 10.1016/j.stemcr.2015.01.021. PubMed PMID:25754203 PubMed Central PMC4400645.
  13. Lindström, NO, Lawrence, ML, Burn, SF, Johansson, JA, Bakker, ER, Ridgway, RA et al.. Integrated β-catenin, BMP, PTEN, and Notch signalling patterns the nephron. Elife. 2015;3 :e04000. doi: 10.7554/eLife.04000. PubMed PMID:25647637 PubMed Central PMC4337611.
  14. Mort, RL, Ford, MJ, Sakaue-Sawano, A, Lindstrom, NO, Casadio, A, Douglas, AT et al.. Fucci2a: a bicistronic cell cycle reporter that allows Cre mediated tissue specific expression in mice. Cell Cycle. 2014;13 (17):2681-96. doi: 10.4161/15384101.2015.945381. PubMed PMID:25486356 PubMed Central PMC4613862.
  15. Lindström, NO, Chang, CH, Valerius, MT, Hohenstein, P, Davies, JA. Node retraction during patterning of the urinary collecting duct system. J. Anat. 2015;226 (1):13-21. doi: 10.1111/joa.12239. PubMed PMID:25292187 PubMed Central PMC4299504.
  16. Lindström, NO, Hohenstein, P, Davies, JA. Nephrons require Rho-kinase for proximal-distal polarity development. Sci Rep. 2013;3 :2692. doi: 10.1038/srep02692. PubMed PMID:24045698 PubMed Central PMC3776198.
  17. Lindström, NO, Neves, C, McIntosh, R, Miedzybrodzka, Z, Vargesson, N, Collinson, JM et al.. Tissue specific characterisation of Lim-kinase 1 expression during mouse embryogenesis. Gene Expr. Patterns. ;11 (3-4):221-32. doi: 10.1016/j.gep.2010.12.003. PubMed PMID:21167960 PubMed Central PMC3407955.
  18. Lee, WC, Hough, MT, Liu, W, Ekiert, R, Lindström, NO, Hohenstein, P et al.. Dact2 is expressed in the developing ureteric bud/collecting duct system of the kidney and controls morphogenetic behavior of collecting duct cells. Am. J. Physiol. Renal Physiol. 2010;299 (4):F740-51. doi: 10.1152/ajprenal.00148.2010. PubMed PMID:20685821 .
  19. Sweeney, D, Lindström, N, Davies, JA. Developmental plasticity and regenerative capacity in the renal ureteric bud/collecting duct system. Development. 2008;135 (15):2505-10. doi: 10.1242/dev.022145. PubMed PMID:18579677 .